GSL’s Targeted Lipid Panels provide advanced, quantitative lipidomics designed to accelerate discovery and clinical development in neurodegeneration, inflammation, and rare disease. Powered by mass spectrometry, AI-driven insights, and decades of scientific expertise, our NeuroLipid capabilities deliver unparalleled depth, accuracy, and reliability, helping our partners uncover meaningful biological signals with confidence.
TARGETED, QUANTITATIVE,
AND DEEPLY INFORMATIVE
Our NeuroLipid Panels enable targeted analysis of 250+ lipids, isoforms, and analogues, supporting both broad discovery projects and highly focused, hypothesis-driven studies.
Markers specifically designed around neurodegenerative disease
Ability to select individual species/isoforms/panels forclinical analysis at a GLP standard
Suitable for clinical and preclinical applications
OUR INDIVIDUAL PANELS
All assays available from non-GLP to GLP standard.
GLYCOSPHINGOLIPIDS AND SPHINGOLIPIDS
HexCer (glucosyl- and galactosylceramide)
CSF, plasma, bloodspots, urine, cells, tissue, animal models
26 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
26 species analysed by LC-MS
Hex2Cer (lactosyl- and galabiosylceramide)
CSF, plasma, bloodspots, urine, cells, tissue, animal models
14 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
14 species analysed by LC-MS
Gb3Cer (globotriaosylceramide)
CSF, plasma, bloodspots, urine, cells, tissue, animal models
20 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
20 species analysed by LC-MS
Gb4Cer (globotetraosylceramide)
CSF, plasma, bloodspots, urine, cells, tissue, animal models
12 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
12 species analysed by LC-MS
Ceramide
CSF, plasma, bloodspots, urine, cells, tissue, animal models
23 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
23 species analysed by LC-MS
Ganglioside
CSF, plasma, bloodspots, cells, tissue, animal models
26 species analysed by LC-MS
CSF, plasma, bloodspots, cells, tissue, animal models
26 species analysed by LC-MS
Sulfatide
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
Sphingomyelin
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
PHOSPHOLIPIDS AND GLYCEROLIPID
Phosphatidylcholine
CSF, plasma, bloodspots, urine, cells, tissue, animal models
25 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
25 species analysed by LC-MS
Phosphatidylethanolamine
CSF, plasma, bloodspots, cells, tissue, animal models
25 species analysed by LC-MS
CSF, plasma, bloodspots, cells, tissue, animal models
25 species analysed by LC-MS
Plasmalogen phosphatidylethanolamine
CSF, plasma, bloodspots, urine, cells, tissue, animal models
28 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
28 species analysed by LC-MS
Cardiolipin (on request)
CSF, cells, tissue, animal models
Analysed by LC-MS
CSF, cells, tissue, animal models
Analysed by LC-MS
Tri-, di- and monoacylglycerides (in development)
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by LC-MS
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by LC-MS
Ceramide
CSF, plasma, bloodspots, urine, cells, tissue, animal models
23 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
23 species analysed by LC-MS
Ganglioside
CSF, plasma, bloodspots, cells, tissue, animal models
26 species analysed by LC-MS
CSF, plasma, bloodspots, cells, tissue, animal models
26 species analysed by LC-MS
Sulfatide
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
Sphingomyelin
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
24 species analysed by LC-MS
CHOLESTEROL AND CHOLESTEROL DERIVATE
Glucosylcholesterol
CSF, plasma, bloodspots, urine, cells, tissue, animal models
Analysed by LC-MS
CSF, plasma, bloodspots, urine, cells, tissue, animal models
Analysed by LC-MS
Cholesterol/cholesterol precursors /phytosterols (on request)
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by GC-MS
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by GC-MS
Full bile acid profile (x30 species, on request)
CSF, plasma, bloodspots, cells, bile, tissue, animal models
Analysed by LC-MS
CSF, plasma, bloodspots, cells, bile, tissue, animal models
Analysed by LC-MS
Oxysterols (in development)
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by LC-MS
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by LC-MS
Cholesterol esters (in development)
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by LC-MS
CSF, plasma, bloodspots, cells, tissue, animal models
Analysed by LC-MS
PANELS CAN EITHER BE RUN INDIVIDUALLY OR
ALL ASSESSED AS PART OF THE NLP
VERSATILE SAMPLE COMPATIBILITY
Our NeuroLipid Panels are validated across a wide range of human and preclinical matrices, including:
HUMAN
Plasma
CSF
Urine
DBS
Tissue (brain, liver)
CSF
Urine
DBS
Tissue (brain, liver)
MOUSE MODELS
Brain tissue
CSF
Plasma
DBS
CSF
Plasma
DBS
CELL MODELS
iPSC-derived neurons
Microglia
Fibroblasts
Neuronal cell models
Microglia
Fibroblasts
Neuronal cell models
